Opportunities for the development of neuroimmune therapies in addiction.

Partial MHC/Neuroantigen Peptide Constructs: A Potential Neuroimmune-Based Treatment for Methamphetamine Addiction

Relapse rates following current methamphetamine abuse treatments are very high (∼40-60%), and the neuropsychiatric impairments (e.g., cognitive deficits, mood disorders) that arise and persist during remission from methamphetamine addiction likely contribute to these high relapse rates. Pharmacotherapeutic development of medications to treat addiction has focused on neurotransmitter systems wit...

Immune Function Genes, Genetics, and the Neurobiology of Addiction

The neuroimmune system (i.e., the immune system and those components of the nervous system that help regulate immune responses), and in particular the innate immune system, play a role in the development of addictions, including alcoholism, particularly in the context of stressful situations. Certain cells of the neuroimmune system are activated both by stress and by environmental factors such ...

Editorial: New Generation of Psychotherapies Inspired by Cognitive Neuroscience Development: Emergence of Neurocognitive Therapies

نقش سلول‌های گلیا در ایجاد دردهای نوروپاتی و بروز پدیده تحمل / پردردی اپیوئیدها

Common cellular and molecular mechanisms are not only involved in the development of neuropathic pain caused by neurological damage but also in the occurrence of the tolerance/hyperalgesia phenomenon caused by chronic use of opioids. It seems that the activation of the neuroimmune system in the brain and spinal cord is one of the most important mechanisms involved in the initiation and mainte...

اثربخشی مداخلات روان شناختی بر پیشگیری از عود اعتیاد: فراتحلیل

Objective: Different studies have been carried out on the effectiveness of psychological therapies in the treatment of addiction and reduction of its long-term complications. This study aimed to aggregate and combine the results of previous studies and to estimate the effectiveness of these therapies in the relapse prevention of drug addiction through meta-analysis method. Method: This meta-ana...